Betty Lou Siefert, 86, of Du Quoin, passed away at 9:45 P.M., Tuesday, June 24, 2025 at the SIH Memorial Hospital in Carbondale.
Betty had worked as a medical assistant for Dr. Thornburg for many years.  She had also worked at Marshall Browning Hospital in Du Quoin.  She was a member of United Methodist Church in Du Quoin.  Betty enjoyed gardening, mowing her yard, and baking.  She was a member of XI OTA Epsilon Sorority.  Betty enjoyed any activity that included her grandchildren.  Betty's favorite thing to do was spend time with her three girls. Whether it was a softball game, swim meet, or a dance competition, Betty made sure to get there early to get a front row seat. She also looked forward to decorating Christmas cookies or dying Easter eggs every year and she was known for her cupcakes. You could find her on any given day sipping on her Coca Cola, eating Cheetos, and laughing with her family.
She was born June 4, 1939 in Cleveland, OH, the daughter of Noble and Charline (Humphrey) Smith.
She married Don E. Siefert on May 9, 1964 in Du Quoin, IL and he survives.
She is survived by her husband of Du Quoin, one daughter - Stephanie Day and husband Joe of Du Quoin, three grandchildren - Sydnie Twillmann and husband Steve of St. Louis, MO, Sadie Day and Rylie Day, both of Du Quoin, numerous nieces, nephews, great nieces and great nephews.
She was preceded in death by her parents, one sister and brother-in-law - Lillian and Lamoyne Rains and many brothers-in-law and sisters-in-law.
Funeral services will be at 11:00 A.M., Saturday, June 28, 2025 at the Searby Funeral Home in Du Quoin with Rev. Ted Clark and Rev. April Turner officiating.
Friends may call from 9 A.M. until the time of service on Saturday.
Burial will be in the Old Du Quoin Cemetery in Du Quoin.
Friends may make memorials to Marshall Browning Hospital Tree of Life and will be accepted at the funeral home.